What is phosphatidylserine powder?
Phosphatidylserine (PS), also known as phosphatidylserine, is a natural phospholipid and an active substance that forms the cell membrane. It has a unique zwitterionic structure, consisting of a hydrophilic head and a hydrophobic tail. The head of phosphatidylserine contains serine residues, and the tail has two long-chain fatty acids. Due to this structure, it plays an important role in cell signaling, membrane protein function regulation, and apoptosis.
It is widely present in human organs, with varying levels of phosphatidylserine (PS) in different organs, including the liver at 3.1%, the heart at 2.7%, the kidneys at 6.4%, the spleen at 8.3%, and the human brain at up to 17.7%. Therefore, phosphatidylserine (PS) is also known as the “brain nutrient”.
The benefits of phosphatidylserine
1. Enhance memory and learning ability
It can maintain the fluidity and stability of nerve cell membranes, promote the synthesis and release of neurotransmitters such as acetylcholine and dopamine, enhance the efficiency of signal transmission between neurons, and thus improve memory and learning abilities.
Research has shown that PS can improve energy metabolism in brain cells, protect neurons from oxidative damage, and reduce the negative effects of stress hormone cortisol on the hippocampus (memory center), especially with potential benefits in alleviating age-related cognitive decline and forgetfulness.
2. Relieve brain fatigue and stress
Phosphatidylserine (PS) regulates the hypothalamic pituitary adrenal axis (HPA axis), inhibits excessive secretion of the stress hormone cortisol, reduces damage to the hippocampus and prefrontal cortex under high stress, and thus alleviates mental fatigue and emotional tension.
At the same time, PS can enhance the energy metabolism efficiency of neuronal mitochondria, maintain cell membrane stability, reduce oxidative stress damage to nerve cells, improve brain oxygen and nutrient delivery, help restore focus and psychological resilience, especially suitable for high-intensity brain use or long-term exposure to stressful environments.
3. Improve athletic performance
Phosphatidylserine (PS) reduces excessive secretion of cortisol after high-intensity exercise by regulating the levels of the stress hormone cortisol, thereby alleviating exercise fatigue and improving physical recovery efficiency.
Research has shown that supplementing with PS can inhibit oxidative stress response caused by intense exercise, protect myocardial and skeletal muscle cells from damage, prolong exhaustive exercise time, accelerate the clearance of metabolic waste (such as lactate and urea), and improve exercise endurance.
In addition, PS maintains cell membrane stability and energy metabolism efficiency, enhances neuromuscular coordination, and indirectly improves exercise performance. Overall, the core role of PS in the field of exercise is reflected in anti-fatigue, promoting recovery, and regulating stress hormones.
4. Improving ADHD in children
Phosphatidylserine (PS) has the potential to alleviate symptoms of ADHD in children by regulating neurotransmitter release, improving cell membrane function, and reducing cortisol levels.
Research has shown that PS, as an important component of neuronal cell membranes, can promote the synthesis and transmission efficiency of neurotransmitters such as acetylcholine and dopamine, thereby enhancing attention and behavioral control. It can inhibit the excessive secretion of stress hormone cortisol, alleviate oxidative stress damage in brain regions such as the hippocampus and prefrontal cortex, and alleviate common emotional fluctuations and learning difficulties in children with ADHD
Although some studies support its safety and effectiveness, more high-quality research is needed to verify its long-term efficacy and individual differences. It is recommended to combine behavioral interventions under the guidance of doctors for comprehensive application.
5. Improve depression and aid sleep
PS can promote the synthesis and release of serotonin, dopamine, etc., enhance neuronal synaptic plasticity, improve emotional regulation ability, and reduce neuroinflammatory reactions associated with depression.
In terms of sleep, PS helps shorten the time to fall asleep and prolong the deep sleep cycle by balancing the cortisol circadian rhythm, reducing the frequency of nighttime awakenings, and increasing the activity of gamma-aminobutyric acid (GABA).
How much phosphatidylserine per day?
If there is a large amount of meat and fish in the diet, the intake of phosphatidylserine is approximately 180 milligrams per day; If the fat content in food is low, the daily intake of phosphatidylserine will be only 100 milligrams, or even less than 50 milligrams.
According to statistics, the difference between the daily intake of phosphatidylserine in normal individuals and the normal demand is between 70-150 milligrams, with vegetarians showing a more significant difference, which can widen to 200-250 milligrams. Considering the above reasons, a normal person needs to supplement 100-300 milligrams of pure phosphatidylserine daily, which is even more important for vegetarians, low-fat or low cholesterol diets, and elderly people with poor digestion and absorption.
In addition, other dietary habits can also lower the levels of phosphatidylserine in the brain. For example, a lack of omega-3 fatty acids (commonly known as DHA) in the diet can reduce the content of phosphatidylserine in the brain by 28%, which in turn affects the function of the hippocampus, commonly known as memory function.
Is phosphatidylserine safe?
In May 2006, it was allowed by the Korea Food and Drug Administration (KFDA) to highlight and promote the functions of PS-added products, such as “improving negative emotions, enhancing memory,” and preventing dementia in the elderly.
In October 2006, it was recognized by the US Food and Drug Administration (FDA) as a GRAS and can be added as a nutritional enhancer in foods such as yogurt, milk powder, bread, and powdered drinks.
It was included in the list of food (non-pharmaceutical) products by the Japanese Food and Drug HBM and passed the individual review of food additives on February 5, 2010.
It was added to the list of new resource foods by the National Health and Family Planning Commission on October 21, 2010, allowing it to be used as a new resource food.
What is phosphatidylserine used for
- Solid food: Generally speaking, PS added to solid food has relatively stable properties, such as fortified choline cereal.
- Beverages: As PS is an active substance, it is recommended to add it to functional beverages.
- Milk: The added PS can enter the fat droplets of milk, avoiding the hydrolysis reaction of PS and ensuring good stability.
- Yogurt: After pasteurization, the drinking yogurt fortified with PS showed no loss of content throughout its shelf life, indicating that PS has strong stability in yogurt.
- Milk powder: PS can be added to adult milk powder and elderly milk powder, and has strong stability.
- Health products: PS can be added to maternal health products such as DHA, and work together with DHA to coordinate and protect the 2A nervous system.
Conclusion
Phosphatidylserine is a nutrient that plays an important role in brain health. Reasonable intake and supplementation of phosphatidylserine can effectively improve brain function, alleviate brain fatigue, repair brain damage, and enhance memory and cognitive abilities.
How to seeking health phosphatidylserine powder?
Runtai Chemical is a professional and reliable Chinese manufacturer of phosphatidylserine with higher purity and lower price for 15 years. If you are interested in our phosphatidylserine, feel free to contact us for free samples!