


N-Ethyl-D-Glucamine with CAS 14216-22-9
What is N-Ethyl-D-Glucamine?
N-Ethyl-D-Glucamine (NEDG) is a specialized derivative of D-glucose that belongs to the glucamine family of compounds. This white to off-white crystalline powder is synthesized through the reductive amination of D-glucose with ethylamine, resulting in a unique chemical structure that combines the properties of both sugar alcohols and amines.
As a multifunctional pharmaceutical intermediate, N-Ethyl-D-Glucamine exhibits excellent water solubility and chemical stability. Its molecular structure features a hydroxyl-rich polyol chain attached to an ethylamino group, making it an ideal building block for various chemical syntheses and formulations. The compound maintains its integrity across a wide pH range and demonstrates good thermal stability, which is essential for industrial processing and pharmaceutical manufacturing.
Runtai Chemical is a professional and reliable China manufacturer of N-Ethyl-D-Glucamine with CAS 14216-22-9 with higher purity and lower price. If you are interested in our N-Ethyl-D-Glucamine, PLS free to contact us for a free sample!
Product Advantages
- Excellent Solubility: Superior water solubility enables easy formulation and processing, reducing production time and improving manufacturing efficiency in aqueous systems.
- Chemical Stability: Demonstrates exceptional stability across various pH ranges and temperatures, ensuring consistent performance and extended shelf life in diverse conditions.
- Biocompatible Properties: Low toxicity profile and good biocompatibility make it suitable for pharmaceutical and cosmetic applications where safety is paramount.
- Versatile Reactivity: The presence of multiple hydroxyl groups and an amino group provides excellent reactivity for various chemical modifications and derivatizations.
N-Ethyl-D-Glucamine Quick details
- Chemical Name:N-Ethyl-D-Glucamine
- CAS No.:14216-22-9
- EINECS: 238-073-8
- Molecular Formula: C8H19NO5
- Molecular weight:209.24
- Appearance:White crystal powder
- Assay:99%
- Synonyms:N-ETHYLGLUCAMINE;N-ETHYL-D-GLUCAMINE;N-ethylgucamine;N-ETHYLGUCAMINE99+%;1-(Ethylamino)-1-deoxy-D-glucitol;1-Ethylamino-1Chemicalbook-deoxy-D-glucitol;(2R,3R,4R,5S)-6-(ethylamino)hexane-1,2,3,4,5-pentol;(2R,3R,4R,5S)-6-(EthylaMino)hexane-1,2,3,4,5-pentaol
N-Ethyl-D-Glucamine Typical Properties
| Item | Specifications | Results |
| Clarity of solution | Clear colorless to pale yellow solution | conforms |
| Appearance | White crystal powder | conforms |
| Purity | ≥99% | 99.9% |
| Melting point | 136-140℃ | 137.3-139.1℃ |
| Loss on drying | ≤1% | 0.2% |
| Specific optical rotation | -16º~ -17º | -16.2º |
| Residue on ignition | ≤0.1% | 0.03% |
| Heavy metals | ≤20ppm | conforms |
| Conclusion | The results conforms with enterprise standards | |
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N-Ethyl-D-Glucamine Applications
- Pharmaceutical Industry: In pharmaceutical manufacturing, N-Ethyl-D-Glucamine serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is particularly valued in the production of antidiabetic drugs, cardiovascular medications, and other therapeutic compounds. The compound’s ability to form stable salts with acidic drugs enhances drug solubility and bioavailability, making it an essential component in drug formulation and development.
- Cosmetics and Personal Care: The cosmetic industry utilizes N-Ethyl-D-Glucamine as a pH adjuster, emulsifier, and skin conditioning agent. Its gentle nature and good skin compatibility make it suitable for skincare products, hair care formulations, and color cosmetics. NEDG helps improve product texture, stability, and sensory properties while maintaining skin-friendly pH levels.
- Chemical Synthesis: As a versatile building block in organic synthesis, N-Ethyl-D-Glucamine facilitates the creation of complex molecules and specialty chemicals. Chemists utilize its reactive functional groups for derivatization reactions, polymer synthesis, and the development of novel compounds with specific properties tailored to industrial needs.
N-Ethyl-D-Glucamine Package & Storage
- Package: 25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
Hot tags
N-Ethyl-D-Glucamine, NEDG, ethyl glucamine, glucamine derivative, pharmaceutical intermediate, chemical supplier, Runtai Chemical, CAS 14216-22-9


