DL-Homocysteine thiolactone Hydrochloride with CAS 6038-19-3
What is DL-Homocysteine thiolactone Hydrochloride?
DL-Homocysteine thiolactone Hydrochloride (CAS 6038-19-3) is the hydrochloride salt form of DL-homocysteine thiolactone — a cyclic thioester derivative of the naturally occurring amino acid homocysteine. The thiolactone ring makes this compound highly reactive toward nucleophiles, particularly lysine residues in proteins, enabling unique conjugation and modification chemistry.
With the molecular formula C₄H₈ClNO₂S and a molecular weight of 169.63 g/mol, it exists as a white to off-white crystalline powder that is freely soluble in water and polar solvents. It is hygroscopic and should be stored in a sealed container at 2–8 °C under dry conditions.
Runtai Chemical supplies DL-Homocysteinethiolactone Hydrochloride with consistent batch quality, supported by full documentation including COA, MSDS, and regulatory compliance certificates for global shipment.
Runtai Chemical is a professional and reliable China manufacturer of DL-Homocysteine thiolactone Hydrochloride with CAS 6038-19-3 with higher purity and lower price. If you are interested in our DL-Homocysteine thiolactone Hydrochloride, PLS free to contact us for a free sample!
Product Advantages
- Reactive Thiolactone Ring: The strained thioester ring readily reacts with primary amines (e.g., lysine residues), enabling efficient protein modification and conjugation reactions.
- Flexible MOQ & Packing: Available from gram-scale samples up to multi-kilogram commercial batches. Custom packing is available upon request to meet your logistics requirements.
- Full Documentation: Every shipment includes Certificate of Analysis (COA), Safety Data Sheet (MSDS/SDS) for quality assurance.
- Global Export Experience: Experienced handling of international chemical shipping regulations with established routes to North America, Europe, Asia, and the Middle East.
- Competitive Factory Price: Direct manufacturer pricing. Volume discounts available for long-term supply agreements or large-quantity orders.
DL-Homocysteine thiolactone Hydrochloride Quick details
- Chemical Name:DL-Homocysteinethiolactone hydrochloride
- CAS No.:6038-19-3
- EINECS: 227-923-3
- Molecular Formula: C4H8ClNOS
- Molecular weight:153.63
- Appearance:White crystals powder
- Assay:98%
- Synonyms:d,l-homocysteinthiolaktonchlorid;[(3R)-2-oxo-3-thiolanyl]ammonium;1,4-thiolactonehydrochloride;DL-3-Aminotetrahydrothiophen-2-oneHydrochlorideDL-2-Amino-4-mercaptobutyricaChemicalbookcid;DL-Homocysteinethiol;3-Aminodihydrothiophen-2(3H)-onehydrochloride;2(3H)-Thiophenone,dihydro-3-amino-,hydrochloride,(+/-);DL-Homocysteinethiolactonehydrochloride,98.5%
DL-Homocysteine thiolactone Hydrochloride Typical Properties
| Item | Specifications | Results |
| Appearance | White crystals powder | Conforms |
| FTIR | Conforms to reference | Conforms |
| Assay | ≥98.5% | 99.93% |
| Iron(Fe) | ≤20ppm | ＜20ppm |
| Heavy metal(Pb) | ≤10ppm | ＜10ppm |
| Melting point | 199-203℃ | 200-201℃ |
| Loss on drying | ≤0.5% | 0.12% |
| Conclusion | The results conforms with enterprise standards | |
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DL-Homocysteine thiolactone Hydrochloride Applications
- Pharmaceutical Synthesis: Used as a key building block in the synthesis of homocysteine-containing drugs, prodrugs, and thiol-reactive pharmaceutical intermediates.
- Protein Modification & Conjugation: Reacts selectively with lysine ε-amino groups to introduce thiol functionality into proteins, antibodies, and peptides for bioconjugate chemistry.
- Biochemical Research: Used to study homocysteine metabolism, cardiovascular disease mechanisms, and sulfur amino acid biochemistry in academic and industrial research laboratories.
- Diagnostic Reagent Manufacturing: Employed in the preparation of reference standards and reagents for clinical diagnostic kits measuring homocysteine levels associated with cardiovascular risk.
- Peptide Chemistry: Serves as a thiolactone-bearing amino acid analog for solid-phase peptide synthesis and structure-activity relationship studies.
- Material Science & Polymer Chemistry: Used in surface functionalization and the preparation of thiol-reactive polymers and hydrogels for biomedical material applications.
DL-Homocysteine thiolactone Hydrochloride Package & Storage
- Package: 25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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