Poly(hexamethylenebiguanide)hydrochloride with Cas 32289-58-0 china manufacturer-Autech industry

Poly(hexamethylenebiguanide)hydrochloride Cas 32289-58-0 china manufacturer-Autech industry

PHMB with Cas 32289-58-0 china manufacturer-Autech industry

Poly(hexamethylenebiguanide)hydrochloride/PHMB with Cas 32289-58-0

What is Poly(hexamethylenebiguanide)hydrochloride?

Polyhexamethylene biguanide hydrochloride solution is a colorless or light yellow transparent liquid, in which the guanidine group has high activity and can make the polymer positively charged. It is easily adsorbed by various bacteria and viruses that are negatively charged, thereby inhibiting the division ability of bacteria and viruses, causing them to lose their reproductive ability. In addition, the thin film formed by the polymer blocks the respiratory channel of microorganisms, causing them to quickly die.

Runtai Chemical’s Polyhexamethylene Biguanide Hydrochloride (PHMB) represents the gold standard in antimicrobial polymer technology. Our pharmaceutical-grade PHMB offers superior broad-spectrum efficacy against bacteria, fungi, and viruses while maintaining excellent safety profiles for human use.

Runtai Chemical is a professional and reliable China manufacturer of Poly(hexamethylenebiguanide)hydrochloride/PHMB Cas 32289-58-0 with higher purity and lower price. If you interest our PHMB, PLS free to contact us for free sample!

Mode of Action

PHMB’s antimicrobial activity is based on its unique cationic polymer structure. The mechanism involves multiple targeted actions:

1. Electrostatic Interaction – Positively charged biguanide groups bind to negatively charged microbial cell membranes
2. Membrane Disruption – Destabilization of phospholipid bilayer integrity
3. Cytoplasmic Leakage – Loss of essential cellular components and ions
4. DNA Binding – Interference with genetic material replication and transcription
5. Metabolic Inhibition – Disruption of essential enzymatic processes

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Poly(hexamethylenebiguanide)hydrochloride/PHMB Quick details

Chemical Name:Poly(hexamethylenebiguanide)hydrochloride
CAS No.:32289-58-0
EINECS: 1308068-626-2
Molecular Formula: (C8H17N5)n.xClH
Molecular weight:213.32312
Appearance:Slightly yellow to colorless & Clear liquid
Assay:20%-22%;99%
Synonyms:PHMB(20%);Polyhexamethyl;PHMB;Biguanide PHMB;Polyhexamethylene biguanidine hydrochloride,~20% in water;PHMB 98%, 20% solution (Polyhexamethylene biguanide hydrochloride);20% solution;

Poly(hexamethylenebiguanide)hydrochloride/PHMB Typical Properties

Item	Specification	Results
Appearance	Slightly yellow to colorless & Clear liquid	Conforms
Purity	20%-22%	20.88%
PH	4.0-5.0	4.51
Density at 20° C	1.040-1.050	1.049
Absorbance	≥400	553.8
Absorbance	1.2-1.6	1.48
Color of solution	30 max	16.7
Conclusion	The results conforms with enterprise standards

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Products Categories

Nutritional Supplements

Food Additives

Cosmetics Raw Materials

Pharmaceutical Intermediates

Organic Intermediates

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Poly(hexamethylenebiguanide)hydrochloride/PHMB Applications

1. Pharmaceutical & Healthcare Applications
Wound Care & Medical Devices

Advanced Wound Dressings: Chronic wound management with biofilm disruption
Surgical Site Protection: Pre and post-operative antimicrobial barriers
Medical Device Coating: Catheter and implant surface treatment
Antimicrobial Hydrogels: Sustained-release wound healing products

Ophthalmic & Contact Lens Solutions

Contact Lens Disinfection: Multi-purpose cleaning and storage solutions
Ocular Irrigation: Safe eye wash and therapeutic rinse products
Acanthamoeba Treatment: Specialized keratitis therapy formulations

2. Personal Care & Cosmetics
Preservation Systems

Broad-Spectrum Preservation: Water-based cosmetic and personal care products
Natural Product Lines: Gentle preservation for organic and sensitive formulations
Baby Care Products: Safe antimicrobial protection for infant skin care

3. Specialized Applications

Oral Care Products: Mouthwash, toothpaste, and dental rinse formulations
Acne Treatment: Antimicrobial cleansers and spot treatments
Deodorant Systems: Long-lasting odor control technology

4. Industrial & Water Treatment
Water System Applications

Swimming Pool Sanitization: Chlorine-free pool and spa water treatment
Cooling Tower Treatment: Industrial water system microbial control
Process Water Disinfection: Food and beverage industry applications
Legionella Prevention: Building water system protection

5. Textile & Material Treatment

Antimicrobial Textiles: Durable fabric treatment for healthcare and sportswear
Carpet and Upholstery: Long-lasting antimicrobial protection
Air Filtration Media: Enhanced filter performance with microbial control

Poly(hexamethylenebiguanide)hydrochloride/PHMB Package & Storage

Package: 25kg/drum;200kg/drum
Storage: Store in a cool place and keep it sealed to avoid direct sunlight.

PHMB with Cas 32289-58-0 china manufacturer-RUNTAI CHEMICAL

Broad-Spectrum Antimicrobial Efficacy

Gram-Positive Bacteria
Staphylococcus aureus (including MRSA strains), Streptococcus pneumoniae, Enterococcus faecalis(including VRE), Bacillus subtilis and spores, Clostridium difficile

Gram-Negative Bacteria
Pseudomonas aeruginosa, Escherichia coli(including ESBL strains), Klebsiella pneumoniae, Acinetobacter baumannii, Salmonella species

Fungi & Yeasts
Candida albicans, Aspergillus niger, Trichophyton mentagrophytes, Penicillium chrysogenum, Saccharomyces cerevisiae

Viruses & Parasites
Influenza A virus (H1N1, H3N2), Hepatitis B virus, Adenovirus, Acanthamoeba castellanii, Norovirus

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