Berberine Hydrochloride with CAS 633-65-8
What is Berberine Hydrochloride?
Berberine Hydrochloride is the salt form of berberine, a naturally occurring isoquinoline alkaloid found in plants such as Coptis chinensis, Berberis vulgaris, and Hydrastis canadensis. The hydrochloride form offers enhanced water solubility and bioavailability compared to pure berberine, making it the preferred choice for pharmaceutical formulation and dietary supplementation.
As a quaternary ammonium salt, Berberine HCl exhibits a characteristic bright yellow color and forms a stable crystalline powder. Extracted primarily from the root and stem bark of Coptis chinensis (Chinese goldthread) and Berberis species.
Runtai Chemical is a professional and reliable China manufacturer of Berberine Hydrochloride with CAS 633-65-8 with higher purity and lower price. If you are interested in our Berberine Hydrochloride, PLS free to contact us for a free sample!
Product Advantages
- Superior Bioavailability: The hydrochloride salt form significantly improves aqueous solubility over free berberine, enhancing absorption and formulation flexibility for capsules, tablets, and liquid dosage forms.
- Natural & Plant-Derived: Extracted from natural botanical sources. Non-synthetic, traceable supply chain with documentation of plant origin.
- Global Export Experience: Experienced handling of international chemical shipping regulations with established routes to North America, Europe, Asia, and the Middle East.
- Competitive Factory Price: Direct manufacturer pricing. Volume discounts available for long-term supply agreements or large-quantity orders.
Berberine Hydrochloride Quick details
- Chemical Name:Berberine hydrochloride
- CAS No.:633-65-8
- EINECS: 211-195-9
- Molecular Formula:C20H18NO4.Cl
- Molecular weight: 371.81
- Appearance:Yellow Crystalline Powder
- Synonyms:TIMTEC-BB SBB006488;NATURAL YELLOW 18 CHLORIDE;NATURAL YELLOW 18;UMBELLATINE;BERBERINE HCL;BERBERINE HYDROCHLORIDE;BERBERIN HCL;BERBERINE HYDROCHLORIDE N-HYDRATE;Berberine HCL
Berberine Hydrochloride Typical Properties
| Item | Specification | Results |
| Assay | ≥98% | 98.8% |
| Appearance | Yellow Crystalline Powder | Complies |
| Odor | Characteristic | Complies |
| Taste | Characteristic | Complies |
| Sieve Analysis | 95% pass 80 mesh | Complies |
| Moisture Content | ≤12% | 10.20% |
| Ash | ≤0.2% | 0.11% |
| As | ≤2ppm | Complies |
| Cadmium | ≤1ppm | Complies |
| Lead | ≤2ppm | Complies |
| Mercury | ≤0.5ppm | Complies |
| Heavy metals | ≤20ppm | Complies |
| Total plate count | ≤10000CFU/g | Complies |
| Salmonella | Negative | Negative |
| Yeast & Mould | ≤1000CFU/g | Complies |
| E.Coli | Negative | Negative |
| Conclusion | The results conforms with enterprise standards | |
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Berberine Hydrochloride Applications
- Pharmaceutical Manufacturing: Used as an active pharmaceutical ingredient (API) in oral medications for metabolic disorders, anti-infective formulations, and gastrointestinal preparations.
- Dietary Supplements & Nutraceuticals: Used in capsules, softgels, and powders targeting blood sugar balance, weight management, cholesterol support, and gut health.
- Cosmetics & Topical Products: Incorporated into anti-acne skincare formulations, anti-inflammatory serums, and topical antibacterial products due to its proven antimicrobial and anti-inflammatory properties.
Berberine Hydrochloride Package & Storage
- Package: 1kg/bag;25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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