Ectoine with CAS 96702-03-3
What is Ectoine?
Ectoine is a naturally occurring cyclic amino acid derivative first isolated from the extremophilic bacterium Halorhodospira halochloris. It acts as a compatible solute — protecting cells from osmotic stress, heat, dehydration, and UV radiation.
Chemically known as (S)-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid, ectoine belongs to the class of “extremolytes” — molecules that stabilize proteins, nucleic acids, and membrane structures under extreme environmental conditions.
Through its unique water-structuring mechanism, ectoine forms a hydration shell around biomolecules, shielding them from damage caused by osmotic stress, heat, cold, UV light, and oxidative agents. This makes it one of the most versatile bioprotective actives available in the specialty chemicals market today.
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Product Advantages
- Superior Moisture Retention: Ectoine’s water-structuring capability creates a stable hydration shell around skin cells and proteins, delivering long-lasting moisturization that outperforms many conventional humectants.
- Cell & Membrane Protection: Protects cellular membranes, proteins, and DNA from environmental stressors, including UV radiation, heat shock, and oxidative damage — making it ideal for anti-aging and barrier-repair formulations.
- Natural & Biocompatible: Derived from naturally occurring extremophilic bacteria. Ectoine is non-toxic, biodegradable, and well tolerated by human skin and biological systems, aligning with clean-label and green chemistry trends.
- Protein Stabilization: Stabilizes enzymes, vaccines, and therapeutic proteins against aggregation and denaturation during storage and processing — a critical property for biopharmaceutical and biotech applications.
- Anti-Inflammatory Action: Clinical studies show ectoine can reduce inflammatory responses in skin triggered by UV-induced or allergen-related stimuli, supporting its use in sensitive skin and dermatological product lines.
Ectoine Quick details
- Chemical Name:Ectoine
- CAS No.: 96702-03-3
- EINECS: 431-910-1
- Molecular Formula:C6H10N2O2
- Molecular weight:142.16
- Appearance: White powder
- Synonyms:(S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLICACID;THP[B];ECTOINE;4-Pyrimidinecarboxylicacid,1,4,5,6-tetrahydro-2-methyl-,(4S)-(9CI);(S)-1,4,5,6-Tetrahydro-2-mChemicalbookethyl-4-pyrimidinecarboxylicacid;NSC614616;Thp(B),(S)-2-Methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylicacid;(4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLICACID
Ectoine Typical Properties
| Item | Specification | Results |
| Appearance | White powder | White powder |
| Purity | ≥99% | 99.85% |
| Specific Rotation | +139°～+145° | +140.3° |
| PH | 6.0-8.0 | 7.0 |
| Loss on drying | ≤0.5% | 0.07% |
| Sulfuric acid ash | ≤0.3% | 0.02% |
| Chloride | ≤0.01% | Conforms |
| Total colones | ≤100CFU/g | Conforms |
| Molds and yeasts | ≤50CFU/g | Conforms |
| Escherichia coli | Negative | Not detected |
| Staphylococcus | Negative | Not detected |
| Cd | ≤5ppm | Conforms |
| As | ≤2ppm | Conforms |
| Pb | ≤10ppm | Conforms |
| Hg | ≤1ppm | Conforms |
| Conclusion | The results conforms with enterprise standards | |
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Ectoine Applications
- Cosmetics & Skincare: Used in anti-aging creams, sunscreens, moisturizers, serums, and sensitive skin formulations for its potent hydrating and skin-barrier reinforcing properties.
- Pharmaceuticals & Therapeutics: Applied in nasal sprays for allergic rhinitis, topical creams for atopic dermatitis, and as a stabilizing excipient in drug formulations and biologic therapies.
- Hair Care Products: Incorporated into shampoos, conditioners, and scalp treatments for their ability to protect hair follicle cells and improve moisture balance under heat and styling stress.
- Ophthalmic Solutions: Formulated in eye drops to protect corneal cells from desiccation and environmental stress, particularly for dry eye syndrome and contact lens solutions.
- Food & Nutraceuticals: Emerging research supports ectoine’s use as a cell-protective dietary supplement and food preservation agent, leveraging its ability to stabilize cellular structures.
Ectoine Package & Storage
- Package:100g/bag; 25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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