Beta-hydroxyisovaleric acid/HMB with Cas 625-08-1

β – Hydroxy – β – methylbutyric acid (HMB) is a natural metabolite of leucine, which has multiple physiological effects such as regulating protein metabolism, anti degradation, and promoting synthesis. Its main application areas include sports nutrition, clinical medicine, animal husbandry, and food for special medical purposes.

Promote muscle growth and reduce muscle breakdown:

HMB promotes protein synthesis by activating the mTOR signaling pathway, while inhibiting the activity of the ubiquitin proteasome system and caspase, reducing muscle protein degradation. It is particularly suitable for resistance training, elderly sarcopenia, and cachexia populations

Improve athletic performance and recovery:

Among athletes or fitness enthusiasts, HMB can reduce muscle damage caused by high-intensity training, accelerate recovery, and improve lean body mass and strength

Anti tumor cachexia and support for chronic wasting diseases:

For patients with muscle wasting caused by tumor, AIDS, COPD, etc., HMB can delay weight loss, improve nitrogen balance, and enhance muscle mass, and often works better with arginine and glutamine

Intervention for sarcopenia in the elderly:

Supplementing HMB in the elderly can prevent muscle loss caused by bed rest or prolonged sitting, and improve physical function indicators such as grip strength and walking speed

Livestock and animal production:

Adding HMB to pig, poultry and other feed can increase piglet birth weight, improve meat quality, enhance immunity, and promote immunoglobulin content in breast milk

As a food additive:

HMB calcium salt (HMB Ca) is approved for use in beverages, dairy products, sports nutrition foods, special medical formula foods, etc., with a recommended daily intake of no more than 6 grams.