With the global aging population and the improvement of people’s living standards, an increasing number of individuals are recognizing the importance of maintaining their health. How to increase energy and delay aging has become a topic of great interest.
Professor David Sinclair from Harvard Medical School believes that supplementing with NMN can restore NAD+ levels and improve multiple indicators of the body. This discovery has raised our expectations for the anti-aging potential of NMN and has received increasing attention.
What is NMN powder？
NMN (β Nicotinamide Mononucleotide) is a naturally occurring biologically active nucleotide derived from ribose and nicotinamide. It is a precursor substance for NAD+ synthesis and an important metabolic intermediate in cells, belonging to the category of vitamin B derivatives.
NAD+ is widely distributed in all cells of the human body and is an essential coenzyme in the body. Metabolism, redox reactions, maintenance and repair of DNA, gene stability, epigenetic regulation, and more all require the involvement of NAD+, which is crucial for maintaining overall health and balance.
Therefore, our body has a high demand for NAD+, which is continuously synthesized, broken down, and recycled in cells to maintain stable cellular NAD+ levels. NAD depletion is a hallmark of aging and many age-related diseases, such as neuromuscular disorders, cardiac metabolic disorders, liver and kidney diseases.
NMN benefits
1. Enhance energy metabolism
NMN significantly enhances energy metabolism efficiency by increasing intracellular NAD+ levels. NAD+ is the core coenzyme of cellular energy metabolism, directly involved in key metabolic pathways such as glycolysis, fatty acid oxidation, and oxidative phosphorylation in mitochondria.
Supplementing with NMN can reverse the decline in NAD+ levels caused by aging, thereby activating mitochondrial function and increasing ATP production capacity, resulting in improved physical strength and endurance.
2. Repair DNA
NMN (β-nicotinamide mononucleotide) plays a central role in DNA repair by increasing intracellular NAD+(nicotinamide adenine dinucleotide) levels.
NAD+, as a key coenzyme, directly activates two important repair mechanisms: one relies on PARP (poly (adenosine diphosphate ribose) polymerase for single strand break repair; The second is dependent on the repair regulation of the Sirtuins protein family, such as SIRT1 and SIRT6.
It can also enhance the efficiency of base excision repair (BER) and homologous recombination repair (HR), and reduce oxidative DNA damage by scavenging free radicals.
3. Antioxidant
NMN exerts significant antioxidant effects through multidimensional mechanisms, with its core being the elevation of intracellular NAD+ levels and activation of key signaling pathways.
Firstly, NMN directly enhances the activity of the antioxidant enzyme system in cells by supplementing NAD+, thereby efficiently clearing free radicals and reducing oxidative stress damage. Secondly, it activates deacetylases such as SIRT1 and SIRT3, protecting mitochondrial function. In addition, it promotes the synthesis of antioxidant factors such as glutathione, forming a systemic defense barrier.
These mechanisms work together to make NMN a potential role in delaying oxidative stress-related aging and diseases.
4. Enhance immunity
NMN can increase the level of NAD+ in immune cells, increase the number of mitochondria, improve mitochondrial efficiency, and facilitate better energy metabolism in immune cells, enabling them to more effectively perform immune defense, immune surveillance, and other functions.
Supplementing it can restore immune cell function to a youthful level, significantly increase antibody production, and improve the clearance efficiency of pathogens such as the influenza virus.
5. Protecting cardiovascular and cerebrovascular health
NMN has multiple effects in cardiovascular protection by increasing intracellular NAD+ levels.
In terms of heart health, it can enhance the heart’s antioxidant and anti-apoptotic abilities, alleviate cardiac fibrosis, and improve left ventricular systolic function. In terms of vascular health, increasing the level of nitric oxide (NO) in endothelial cells promotes vascular dilation and inhibits the release of inflammatory factors, resulting in a significant improvement in blood pressure.
By improving cellular metabolism and function, it protects the heart and blood vessels, including improving endothelial function and reducing the risk of cardiovascular disease.
NMN side effects
Current research indicates that NMN is well-tolerated in humans, with no severe adverse effects reported in clinical trials. Minor issues like transient metabolic adjustments (e.g., increased energy) can be managed through dosage optimization. Always recommend starting with 400–500 mg/day and consulting healthcare providers for specific populations.
Why Choose Our NMN Powder?
1. Reliable supplier
Runtai Chemical is a professional dietary supplement raw material supplier, providing high-purity products with a purity of up to 99% β-Nicotinamide Mononucleotide（CAS：1094-61-7）. We can ensure to provide you with reliable, quality products for your production or research.
2. Production and safety
Our NMN adopts enzyme-catalyzed synthesis technology to ensure optimal bioavailability. Our factory follows Global Good Manufacturing Practices (GMP) and ensures safety and traceability through third-party certification.
3. service and care
After receiving inquiries, we will implement a quick processing mechanism and arrange for business managers to communicate. Meet all aspects of customer satisfaction, including sample testing, logistics, transportation, and after-sales processing.
Where to buy NMN powder?
Runtai Chemical is a professional and reliable Chinese manufacturer of nmn with higher purity and lower price for 15 years. If you are interested in our NNM, feel free to contact us for free samples!
