Nattokinase with CAS 133876-92-3
What is Nattokinase?
Nattokinase is a serine protease enzyme extracted and purified from soybeans fermented with Bacillus subtilis var. natto — the same fermentation used to make Japan’s traditional natto. First isolated in 1980, it has since become one of the most widely studied natural ingredients associated with healthy blood flow.
Mechanistically, nattokinase directly hydrolyzes fibrin — the structural protein that forms blood clots — and also supports the body’s own plasminogen-to-plasmin pathway. This dual fibrinolytic action is why it is formulated into cardiovascular support products worldwide.
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Product Advantages
- Cardiovascular Support: Promotes healthy blood circulation and supports cardiovascular function through natural fibrinolytic activity.
- Natural Blood Thinner: Demonstrates potent ability to break down fibrin in blood clots, supporting the body’s natural clot-dissolving mechanisms.
- Blood Pressure Support: may help maintain healthy blood pressure levels through ACE inhibition and improved circulation
- Brain Health: Supports cognitive function and may help protect against age-related decline.
- DVT Prevention: supporting healthy blood flow and preventing abnormal clot formation.
- Natural & Safe: Well-tolerated with minimal side effects when used appropriately.
Nattokinase Quick details
- Chemical Name: Nattokinase
- CAS No.:133876-92-3
- EINECS: 229-880-6
- Molecular Formula: N/A
- Molecular weight: N/A
- Appearance: Light yellow powder
- Synonyms: Nattokinase powder, Nattokinase CAS 133876-92-3, Nattokinase manufacturer, bulk Nattokinase supplier, fibrinolytic enzyme, Nattokinase raw material, OEM Nattokinase capsules
Nattokinase Typical Properties
| Item | Specification | Results |
| Appearance | Yellow powder | Conforms |
| Activity of enzyme | 2000 Fu/g | 2130Fu/g |
| Loss on drying | ≤ 5% | 3.1% |
| Residue on ignition | ≤ 5% | 2.3% |
| Heavy metas(Pb) | ＜5ppm | ＜5ppm |
| Heavy metals(As) | ＜3ppm | ＜3ppm |
| Total bacterial count | ≤1000CFU/g | Conforms |
| TE | <30CFU/g | <30CFU/g |
| Total yeast and mold | <100CFU/g | <10CFU/g |
| E.Coliforms | Absent in 25g | N.D. |
| Salmonella | Absent in 25g | N.D. |
| Conclusion | The results conforms with enterprise standards | |
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Nattokinase Applications
- Dietary Supplements: Formulated into capsules, tablets, and powders for cardiovascular health support, typically at 100-200mg (2,000-4,000 FU) daily dosage.
- Functional Foods: Incorporated into health beverages, fortified foods, and nutritional bars targeting heart health and active aging populations.
- Pharmaceutical Research: Under investigation (Phase II clinical trials) as an oral antithrombotic agent for preventing cardiovascular diseases and stroke.
- Sports Nutrition: Used in performance supplements to support circulation, reduce muscle soreness, and enhance recovery through improved blood flow.
- Anti-Aging Products: Featured in longevity and healthy aging formulations due to cardiovascular and potential neuroprotective benefits.
- Combination Therapies: Often combined with red yeast rice, CoQ10, omega-3, or other cardiovascular support ingredients for synergistic effects.
Nattokinase Package & Storage
- Package: 1kg/bag;25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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,CAS 133876-92-3
