

Melatonin with CAS 73-31-4
What is Melatonin?
Melatonin (also spelled Melatonine, CAS 73-31-4) is a naturally occurring indoleamine hormone primarily synthesized and secreted by the pineal gland. It plays a central role in regulating the human circadian rhythm — the body’s internal biological clock — in response to light and darkness cycles.
Runtai Chemical provides pharmaceutical-grade Melatonin raw material powder with exceptional purity, meeting the requirements of major international pharmacopeias, including USP, EP, and CP. Our Melatonin is widely used as an active pharmaceutical ingredient (API), a dietary supplement ingredient, and a functional cosmetic raw material.
Runtai Chemical is a professional and reliable China manufacturer of Melatonin with CAS 73-31-4 with higher purity and lower price. If you are interested in our Melatonin, PLS free to contact us for a free sample!
Product Advantages
- GMP-Certified Manufacturing: Manufactured under Good Manufacturing Practice (GMP) conditions with full documentation, CoA, MSDS, and technical data sheet provided for every shipment.
- Stable Global Supply: Consistent inventory with flexible packaging from 1 kg to bulk 25 kg drums. Reliable lead times and professional export logistics to Gables countries.
- Circadian Rhythm Regulation: The most evidence-backed ingredient for sleep phase regulation. Clinically studied for jet lag, shift-work disorder, and insomnia — supporting premium product formulations.
- Powerful Antioxidant Profile: Melatonin exhibits direct free-radical scavenging activity and stimulates endogenous antioxidant enzymes, making it highly valuable in anti-aging and neuroprotective formulations.
Melatonin Quick details
- Chemical Name:Melatonine
- CAS No.:73-31-4
- EINECS:200-797-7
- Molecular Formula:C13H16N2O2
- Molecular weight:232.28
- Appearance:White to off-white crystal powder
- Assay:98.5-101.5%
- Synonyms:Melatonin(AS);Melatonine,N-(2-(5-Methoxyindol-3-yl)ethyl)acetaMide;MELATONINEFORSYNTHESIS1G;MELATONINEFORSYNTHESIChemicalbookS5G;Melatoninsolution;N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE;N-(2-(5-methoxyindol-3-yl)ethyl)acetamide;MLT
Melatonin Typical Properties
| Item | Specification | Results |
| Characteristics | A White or off-white crystalline powder | conforms |
| Infrared absorption | Positive | Positive |
| Ultraviolet absorption | Positive | Positive |
| HPLC identification test | Positive | Positive |
| Loss on drying | 1.0% max | 0.15% |
| Residue on ignition | 0.1% max | 0.04% |
| Melting point | 116.0-120.0℃ | 117.6-118.8℃ |
| Chloride and Sulfate | ≤0.2%
|
pass |
| As | ≤1ppm | pass |
| Cd | ≤1ppm | pass |
| Hg | ≤0.1ppm | pass |
| Pb | ≤1ppm | pass |
| Individual impurity | ≤0.1%
|
0.04% |
| Total impurities | ≤1.0%
|
0.17% |
| Purity
|
98.5-101.5% | 99.8% |
| Conclusion | Comply with the requirement usp43 | |
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Melatonin Applications
- Pharmaceutical: Used as API in OTC and Rx sleep disorder medications, circadian rhythm treatments, and adjunct therapy for certain neurological conditions. Meets pharmacopeial specifications.
- Nutraceuticals & Supplements: Primary ingredient in sleep support supplements, tablets, capsules, gummies, sublingual drops, and functional foods. Leading seller in global health & wellness retail.
- Cosmetics & Skincare: Incorporated into anti-aging serums, night creams, and eye treatments for its potent antioxidant and skin-barrier restoration properties. Growing demand in premium cosmetic lines.
Melatonin Package & Storage
- Package: 1kg/bag;25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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