β-Nicotinamide adenine dinucleotide CAS 53-84-9
What is β-Nicotinamide adenine dinucleotide?
β-Nicotinamide adenine dinucleotide (NAD+), also known as pyridine diphosphate nucleotide (DPN), is used as a coenzyme in redox reactions, as a donor for the ADP ribose moiety in ADP ribosylation reactions, and as a precursor for the second signaling molecule ring ADP ribose. beta- nicotinamide adenine dinucleotide also serves as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins, which use NAD+to remove acetyl groups from proteins.
Beta-Nicotinamide Adenine Dinucleotide (NAD+) is a vital coenzyme found in all living cells, playing a key role in energy production and cellular repair. It is essential for metabolic processes, including glycolysis, the citric acid cycle, and oxidative phosphorylation, which convert nutrients into ATP, the body’s primary energy currency. NAD+ also supports DNA repair and activates sirtuins, proteins that regulate aging and cellular health.
Supplementing with NAD+ precursors, like nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), has gained popularity for its potential to combat aging, boost energy levels, and enhance cognitive function. Research suggests NAD+ may improve mitochondrial function, reduce inflammation, and support overall vitality, making it a promising tool for promoting longevity and wellness.
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NAD+ Cellular Mechanisms
Energy Production:
• Glycolysis pathway acceleration
• Krebs cycle optimization
• Electron transport chain enhancement
• ATP synthesis maximization
DNA Repair & Protection:
• PARP enzyme activation
• Sirtuin pathway stimulation
• Telomere length maintenance
• Oxidative stress reduction
β-Nicotinamide adenine dinucleotide Quick Details
- Chemical Name:β-Nicotinamide adenine dinucleotide
- CAS No.: 53-84-9
- EINECS: 200-184-4
- Molecular Formula: C21H27N7O14P2
- Molecular weight: 663.43
- Appearance:White powder
- Assay: 99%min
- Synonyms:-NicotinaMideadeninedinucleotide,diphosphopyridinenucleotide;β-NicotinaMideAdenineDinucleotideHydrate,oxidizedforM[forBiocheMicalResearch];beta-DiphosphopyridinenucleotideSynonyMsbeta-NicotinaMideadeninedinucleotide;adenosine5′-(trihydrogendiphosphate)P’Chemicalbook→5′-esterwith3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium,innersalt;OSTEOPONTIN,GSTFUSION;)-1-beta-d-ribofuranosylpyridiniumhydroxide,innersalt;adenine-nicotinamidedinucleotide;adenosine5’-(trihydrogendiphosphate),p’.fwdarw.’-esterwith3-(aminocarbonyl;beta-Nicotinamide adenine dinucleotide
β-Nicotinamide adenine dinucleotide Typical Properties
| Item | Specification | Results |
| Appearance | White powder | Conforms |
| Purity | ≥99% | 99.81% |
| Assay | ≥99% | 99.61% |
| Water | ≤8% | 5.1% |
| Sodium contents | ≤1.0% | 0.025% |
| PH | 2.0-5.0 | 3.1 |
| Pb | ≤0.5ppm | <0.5ppm |
| As | ≤0.5ppm | <0.5ppm |
| Cd | ≤0.5ppm | <0.5ppm |
| Hg | ≤0.5ppm | <0.5ppm |
| Total Plate count | ≤750cfu/g | Conforms |
| Yeast and Mould | ≤100cfu/g | Conforms |
| Salmonella | N.D. | N.D. |
| E. Coli | N.D. | N.D. |
| Staphylococcus aureus | N.D. | N.D. |
| Conclusion | The results conforms with USP standards | |
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β-Nicotinamide adenine dinucleotide Applications
Neurological & Cognitive Health: Supports mitochondrial function in neurons, enhances synaptic plasticity, reduces neuroinflammation
- Alzheimer’s disease research
- Parkinson’s disease studies
- Cognitive enhancement protocols
- Neuroprotection mechanisms
- Memory and learning enhancement
Cardiovascular & Metabolic Health: Improves endothelial function, enhances insulin sensitivity, supports cardiac muscle metabolism
- Heart failure intervention studies
- Diabetes mellitus research
- Metabolic syndrome treatment
- Hypertension management
- Atherosclerosis prevention
Exercise Performance & Recovery: Enhances mitochondrial biogenesis, improves oxygen utilization, accelerates lactate clearance
- Athletic performance enhancement
- Exercise-induced fatigue reduction
- Muscle recovery acceleration
- Endurance capacity improvement
- Age-related muscle decline prevention
Longevity & Anti-Aging Research: Activates longevity genes (sirtuins), enhances DNA repair, reduces cellular damage accumulation
- Cellular senescence reversal
- Telomere length preservation
- Skin aging prevention
- Immune system rejuvenation
- Healthspan extension studies
β-Nicotinamide adenine dinucleotide Package&Storage
- Package: 1KG/BAG;25kg/drum
- Storage: -20°C for long-term, 2-8°C short-term
- Stability: 24 months at -20°C
- Light sensitivity: Store in dark containers
- Reconstitution: Use sterile water or PBS
