5-Hydroxytryptophan (5-HTP) with CAS 4350-09-8
What is 5-Hydroxytryptophan?
5-Hydroxytryptophan (5-HTP), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor in the biosynthesis of serotonin and melatonin. As an intermediate in the metabolic pathway from tryptophan to serotonin (5-hydroxytryptamine), 5-HTP readily crosses the blood-brain barrier, making it a highly bioavailable ingredient for supporting neurotransmitter balance.
In the body, L-Tryptophan is converted to 5-HTP by the enzyme tryptophan hydroxylase. 5-HTP is then decarboxylated by aromatic amino acid decarboxylase into serotonin. This direct precursor role makes 5-HTP a strategically important active pharmaceutical and nutraceutical ingredient.
Runtai Chemical is a professional and reliable China manufacturer of 5-Hydroxytryptophan (5-HTP) with CAS 4350-09-8 with higher purity and lower price. If you are interested in our 5-Hydroxytryptophan (5-HTP), PLS free to contact us for a free sample!
Product Advantages
- High Purity: HPLC-verified purity in every batch. Our stringent QC process ensures a consistently clean product free from impurities and by-products.
- GMP Manufacturing: Produced in ISO-certified, GMP-compliant facilities. Full traceability from raw material to finished product with batch records available.
- Complete Documentation: Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and custom documentation available for every order. Audit-ready paperwork.
- Flexible MOQ & Packaging: Starting from 1 kg samples up to multi-ton bulk orders. Customized packaging options available to meet your specific labeling requirements.
5-Hydroxytryptophan Quick details
- Chemical Name:L-5-Hydroxytryptophan
- CAS No.:4350-09-8
- EINECS: 224-411-1
- Molecular Formula: C11H12N2O3
- Molecular weight:220.22
- Appearance:White powder
- Synonyms:5-hydroxy-l-tryptopha;pretonine;L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONICACID;L-5-HYDROXYTRYPTOPHANHYDRATE;ChemicalbookL-5-HYDROXYTRYPTOPHAN;L-5-HTP;2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPIONICACID;(-)-5-HYDROXY-L-TRYPTOPHAN
5-Hydroxytryptophan Typical Properties
| Item | Specification | Results |
| Appearance | White to Off-white Powder | Complies
|
| Solubility10mg/ml | Clear and transparent, without obvious insolubles | Complies |
| IR Identification | Spectrum must conform | Complies
Reference Spedrum |
| Particle size | 98% pass 80 mesh | Complies |
| Loss on drying | ≤0.5% | 0.07% |
| Residue on ignition | ≤0.3% | 0.05% |
| PH | 4.5～6.5 | 5.58 |
| Optical Rotation | -30.0 º～-35.0º | -32.22º |
| Heavy Metal | ≤10ppm | Complies |
| Pb | ≤0.5ppm | Complies |
| As | ≤0.5ppm | Complies |
| Cd | ≤0.1ppm | Complies |
| Hg | ≤0.1ppm | Complies |
| Assay | ≥99%min | 99.67% |
| DBP | ≤0.3ppm | Complies |
| Total Impurities | ≤0.3% | 0.12% |
| Peak X | Complies | Complies |
| Total plate count | ≤1000CFU/g | <1 |
| Yeast & Mould | ≤100CFU/g | <1 |
| E.Coli | Absent/25 | Absent |
| Salmonella | Absent/10 | Absent |
| Conclusion | The results conforms with USP standards | |
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5-Hydroxytryptophan Applications
- Dietary Supplements & Nutraceuticals: Widely used in sleep support, mood balance, and stress relief supplements. A top-selling ingredient in capsule, tablet, and powder formats for the global wellness market.
- Pharmaceutical Research: Used as a reference standard and active ingredient in clinical research related to depression, anxiety, fibromyalgia, and neurodegenerative conditions.
- Sleep & Melatonin Formulations: As a precursor to both serotonin and melatonin, 5-HTP is a key ingredient in sleep formula stacks, often combined with L-theanine, magnesium, and GABA.
- Weight Management Products: 5-HTP supports appetite regulation through serotonergic pathways. Used in weight management formulas to help promote satiety and reduce carbohydrate cravings.
- Nootropics & Cognitive Health: A staple in nootropic stacks aimed at mood enhancement, stress reduction, and overall cognitive well-being. Popular in pre-workout and post-workout recovery products.
5-Hydroxytryptophan (5-HTP) Package & Storage
- Package: 1kg/bag;25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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