Benfotiamine with Cas 22457-89-2
What is Benfotiamine?
As a pharmaceutical intermediate, benfotiamine is used to produce fat soluble derivatives of thiamine and other drugs. Because of its high bioavailability, it is widely used to prevent and treat vitamin B1 deficiency, diabetes and its complications (such as neuropathy, nephropathy, retinopathy), and to alleviate alcoholic neurological damage, cognitive impairment of senile dementia and improve cardiovascular health.
Benzotimine (S-Benzoylthiamine O-monophosphate) is a fat soluble analogue of vitamin B1, which has a higher absorption rate and bioavailability than vitamin B1, and is commonly used as a food supplement for diabetes complications. Benfotiamine has direct antioxidant capacity and can prevent DNA damage.
Runtai Chemical is a professional and reliable China manufacturer of Benfotiamine with Cas 22457-89-2 with higher purity and lower price. If you interest our Benfotiamine with Cas 22457-89-2 , PLS free to contact us for free sample!
Recommended
Dosage:(exact dosage should be subject to customer’s finial product formulation.)
Benfotiamine Quick details
- Chemical Name:Benfotiamine
- CAS No.: 22457-89-2
- EINECS: 245-013-4
- Molecular Formula:C19H23N4O6PS
- Molecular weight:466.45
- Appearance: White crystal or white crystalline powder
- Synonyms:berdi;betivina;benphothiamine;BENFOTAMINE(S-BENZOYLTHIAMINE-O-MONOPHOSPHATE);S-[2]-[(4-Amino-2-methyl-5-pyrimidinyl)methy-[formylamino]-1-[2-phosphonoxy)ethyl]-1-propenyloicesterphenylcarbathionoicacid;ThiobenzoicacidS-[2Chemicalbook-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propenyl]ester;ThiobenzoicacidS-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-5-(phosphonooxy)-2-penten-3-yl]ester;Benfotiamine
Benfotiamine Typical Properties
| Item | Specification | Results |
| Description
|
White crystal or white crystalline powder
|
White crystalline
powder
|
| Identification | The retention time of main peak is
accordant with that of Benfotiamine RS
|
conforms |
| Melting point
|
≥198℃
|
203~206℃
|
| Loss on drying
|
≤1.2%
|
0.4%
|
| Clarity and color of solution
|
Colorless to light yellow clear solution
|
Colorless and clear solution
|
| Chloride
|
≤0.053%
|
<0.053%
|
| Sulphate
|
≤0.011%
|
<0.011%
|
| Heavy metals
|
≤20ppm
|
<20ppm
|
| Cd
|
≤1ppm
|
0.042ppm
|
| As
|
≤1ppm
|
<0.01ppm
|
| Pb
|
≤0.5ppm
|
<0.02ppm
|
| Hg
|
≤0.3ppm
|
<0.005ppm
|
| Bulk density
|
≥0.35g/ml
|
0.50g/ml
|
| Thiamine
|
≤0.1%
|
0.09%
|
| Benzoic acid
|
≤0.1%
|
0.01%
|
| Total impurities
|
≤0.1%
|
0.3%
|
| Assay
|
98.0%-102.0%
|
100.8%
|
| Total Plate Count
|
≤1000CFU/g
|
＜10CFU/g
|
| Yeast & Mold
|
≤100CFU/g
|
＜10CFU/g
|
| Salmonella
|
Negative
|
Negative
|
| E.Coli
|
Negative
|
Negative
|
| Staphylococcus Aureus
|
Negative
|
Negative
|
| Conclusion | The results conforms with enterprise standards | |
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Benfotiamine Applications
Treatment of complications of diabetes: Benfotiamine can inhibit the formation of advanced glycation end products (AGEs), and effectively treat neuralgia, peripheral neuritis, peripheral nerve paralysis, nephropathy and retinopathy caused by diabetes.
Vitamin B1 deficiency: Benfotiamine is used to supplement thiamine deficiency caused by insufficient daily dietary intake (such as fatigue, pregnancy, lactation, intense labor), as well as neurological damage caused by alcohol poisoning.
Neurological and chronic disease adjuvant therapy: Due to its easy penetration of cell membranes, Benfotiamine is commonly used to treat neuropathic pain, muscle pain, joint pain, and myocardial metabolic disorders.
Brain health and cognitive improvement: Studies have shown that benfotiamine can help maintain brain health and may assist in alleviating memory decline in Alzheimer’s disease (senile dementia).
Phenylphosphoramine generally has good tolerance and is suitable as a highly efficient thiamine supplement
Benfotiamine Package & Storage
- Package:1kg/bag; 25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
FAQ
Q: Are you factory/manufacturer of Benfotiamine ?
A: yes, we are china factory of Benfotiamine , Runtai chemical has been committed to the production and export of Benfotiamine with high quality to United States, Japan, Europe, South Africa, Taiwan, etc…
Q: Does the free sample avaiable?
A:Yes,we can provide free samples for you before you buy commercial quantity.
Q: What’s the advantages of Benfotiamine ?
A:Benfotiamin is a fat soluble analogue of vitamin B1, with higher absorption and bioavailability than vitamin B1. Benfotiamin has direct antioxidant capacity and can prevent DNA damage
Q: What are the packaging options available?
A: We offer packaging according your request, our regular package is 25kg/drum
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