L-Carnosine with CAS 305-84-0
What is L-Carnosine?
L-Carnosine (β-Alanyl-L-Histidine) is a naturally occurring dipeptide composed of the amino acids beta-alanine and L-histidine. It is found in high concentrations in skeletal muscle, cardiac muscle, and brain tissue of vertebrates, where it plays a critical role in cellular defense and pH buffering.
L-Carnosine was first discovered in the early 20th century and has since been the subject of extensive scientific research. Its multifunctional bioactivity—spanning antioxidant, anti-glycation, metal-chelating, and pH-buffering mechanisms—makes it one of the most versatile naturally derived active ingredients in the specialty chemicals market.
Our L-Carnosine is synthesized under strictly controlled GMP conditions and undergoes rigorous QC testing at every production stage, suitable for pharmaceutical-grade, food-grade, and cosmetic applications, ensuring the highest standards for our global customers.
Runtai Chemical is a professional and reliable China manufacturer of L-Carnosine with CAS 305-84-0 with higher purity and lower price. If you are interested in our L-Carnosine, PLS free to contact us for a free sample!
Product Advantages
- Powerful Antioxidant: L-Carnosine effectively scavenges reactive oxygen species (ROS) and free radicals, protecting cells from oxidative stress and damage.
- Anti-Glycation Activity: Inhibits the formation of Advanced Glycation End-products (AGEs), which accumulate with age and are linked to neurodegenerative diseases, diabetes complications, and skin aging.
- Metal Ion Chelation: Chelates transition metals such as copper, zinc, and iron, preventing metal-catalyzed oxidative reactions that damage proteins and nucleic acids.
- pH Buffering in Muscle: Acts as a physiological pH buffer in skeletal muscle, delaying the onset of fatigue during high-intensity exercise by neutralizing lactic acid accumulation.
- Neuroprotective Effects: Research supports L-Carnosine’s role in protecting neuronal cells from oxidative damage, with potential benefits in cognitive health and neurodegenerative conditions.
- Skin Rejuvenation: Promotes collagen synthesis, inhibits cross-linking of skin proteins, and helps maintain youthful skin structure.
L-Carnosine Quick details
- Chemical Name:L-Carnosine
- CAS No.: 305-84-0
- EINECS: 206-169-9
- Molecular Formula:C9H14N4O3
- Molecular weight:226.23
- Appearance:White of off-white powder
- Assay:99%
- Synonyms:N-B-ALANYL-L-HISTIDINE;H-BETA-ALA-HIS-OH;L-IGNOTINE;L-BETA-ALANINE HISTIDINE;L-CARNOSINE;B-ALANYL-L-HISTIDINE;BETA-A-H;BETA-ALANYL-L-HISTIDINE
L-Carnosine Typical Properties
| Item | Specification | Results |
| Appearance | White of off-white powder
|
Conforms |
| HPLC Identification | Consistent with the reference substance main peak retention time | Conforms |
| Purity | 99.0%-101.0% | 99.85% |
| Heavy metal | ≤10ppm | Conforms |
| Specific rotation | ＋20℃～＋22℃ | ＋21.6℃ |
| PH | 7.5-8.5 | 8.0 |
| Loss on drying | ≤1.0% | 0.10% |
| Lead | ≤3ppm | Conforms |
| Arsenic | ≤1ppm | Conforms |
| Cadmium | ≤1ppm | Conforms |
| Mercury | ≤0.1ppm | Conforms |
| Residue on ignition | ≤0.1% | 0.01% |
| Hydrazine | ≤2ppm | Conforms |
| Melting point | 250.0℃-265.0℃ | 255.0℃-256.6℃ |
| Bulk density | — | 0.24g/ml |
| Tapped density | — | 0.51g/ml |
| L-Histidine | ≤0.3% | 0.05% |
| Total aerobes counts | ≤1000CFU/g | 42CFU/g |
| Mold &Yeast | ≤100CFU/g | CFU/g |
| E.Colo | negative | Not detectable |
| Salmonella | negative | Not detectable |
| Conclusion | The results conforms with enterprise standards | |
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L-Carnosine Applications
- Pharmaceutical & Nutraceuticals: Used as an active pharmaceutical ingredient in anti-aging drugs, neuroprotective formulations, eye drop solutions for cataracts (N-Acetylcarnosine), and gastrointestinal health products.
- Sports Nutrition & Supplements: A popular ingredient in pre-workout formulas, endurance supplements, and muscle recovery products. Reduces exercise-induced oxidative stress and supports muscle buffering capacity.
- Cosmetics & Skincare: Incorporated into premium anti-aging serums, creams, and skin treatments. Reduces glycation-induced skin damage, supports collagen integrity, and provides antioxidant protection against UV stress.
- Veterinary & Pet Nutrition: Increasingly used in premium pet food supplements and veterinary applications to support healthy aging, joint health, and cognitive function in companion animals.
L-Carnosine Package&Storage
- Package: 25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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Introduction L-Carnosine is a naturally occurring dipeptide composed of β-alanine and L-histidine, widely distributed in human muscle and brain tissues. […]
