S-Adenosyl-L-methionine Disulfate Tosylate with CAS 97540-22-2
What is S-Adenosyl-L-methionine Disulfate Tosylate?
S-Adenosyl-L-methionine Disulfate Tosylate (SAMe Disulfate Tosylate), with CAS number 97540-22-2, is a highly stable salt form of S-adenosylmethionine (SAMe) — one of the most important endogenous compounds involved in methyl group transfer reactions in the human body. This disulfate tosylate salt form is widely recognized as the gold standard for pharmaceutical and nutraceutical formulations due to its superior stability compared to other SAMe salt forms.
SAMe is a naturally occurring molecule found in virtually all living organisms. It serves as a key methyl donor in transmethylation reactions, participating in over 100 enzymatic reactions including the biosynthesis of neurotransmitters, hormones, proteins, phospholipids, and nucleic acids. The Disulfate Tosylate formulation significantly improves the shelf life and bioavailability of SAMe, making it ideal for industrial-scale pharmaceutical manufacturing.
Runtai Chemical supplies S-Adenosyl-L-methionine Disulfate Tosylate under stringent GMP-certified conditions. Our product is available in bulk quantities with full documentation including Certificate of Analysis (COA), MSDS, and third-party testing reports to meet global regulatory requirements.
Runtai Chemical is a professional and reliable China manufacturer of S-Adenosyl-L-methionine Disulfate Tosylate with CAS 97540-22-2 with higher purity and lower price. If you are interested in our S-Adenosyl-L-methionine Disulfate Tosylate, PLS free to contact us for a free sample!
Product Advantages
- Exceptional Chemical Stability: The disulfate tosylate salt form is the most stable commercially available form of SAMe, offering significantly extended shelf life and resistance to oxidation compared to butanedisulfonate forms.
- Superior Bioavailability: Highly bioavailable formulation ensures efficient absorption in the gastrointestinal tract, maximizing therapeutic efficacy in pharmaceutical and dietary supplement applications.
- Flexible Supply Quantities: From 100g research samples to metric-ton bulk orders, Runtai Chemical provides flexible supply options with consistent quality across all batch sizes and reliable lead times.
- Full Regulatory Documentation: Complete documentation package available including COA, MSDS/SDS, third-party testing reports, and export documentation to facilitate global customs compliance.
S-Adenosyl-L-methionine Disulfate Tosylate Quick details
- Chemical Name:S-Adenosyl-L-methionine Disulfate Tosylate
- CAS No.:97540-22-2
- EINECS: 249-946-8
- Molecular Formula: C22H34N6O16S4
- Molecular weight:766.78
- Appearance:White or almost white crystalline powder
- Assay:99%
- Synonyms:SAM-T(S-Adenosyl-5-L-MethionineTosylate);S-Adenosyl-L-Methioninedisulfatetosylate(SAM-T);S-adenisyl-L-Methioninedisulfate-p-toluenesulfonate;SAM-T;AdeMethionineDisulfateTosylate;S-Adenosyl-L-MethioninChemicalbookeDisulfatep-Toluenesulfonate(MixtureofDiastereomers);AdemetioninedisulfatetosylateS-Adenosyl-L-methioninedisulfatetosylate;AdemetionineDisulfateTosylate(500mg)(S-Adenosyl-L-MethionineDisulfateTosylate)
S-Adenosyl-L-methionine Disulfate Tosylate Typical Properties
| Item | Specification | Results |
| Appearance | White or almost white crystalline powder | Conforms |
| Identification | Conforms to the Reference Spectrum
The retention time of the major peak corresponds to the reference sample |
Conform |
| Assay | 95.0%-105% | 101.80% |
| SAM-e ION (HPLC) | 49.5% – 54.7% | 53.2% |
| P-Toluenesulfonic Acid | 21.0%–24.0% | 22.5% |
| Content of Sulfate (SO4)（LC） | 23.5%–26.5% | 25.2% |
| S, S-Isomer (HPLC) | ≥60% | 83% |
| PH | 1.0-2.0 | 1.2 |
| Water | ≤3.0% | 0.5% |
| Residue on ignition | ≤0.5% | 0.1% |
| S-Adenosyl-L-Homocysteine | ≤1.0% | 0.0% |
| Adenine | ≤1.0% | 0.2% |
| Methylthio Adenosine | ≤1.5% | 0.2% |
| Adenosine | ≤1.0% | 0.0% |
| Total Impurities | ≤3.5% | 2.5% |
| Heavy Metals | ≤10ppm | Conform |
| Lead | ≤3ppm | Conform |
| Cadmiun | ≤1ppm | Conform |
| Mercury | ≤1ppm | Conform |
| Arsenic | ≤2ppm | Conform |
| Total Aerobic Count | ≤1000cfu/g | Conform |
| Conclusion | The results conforms with enterprise standards | |
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S-Adenosyl-L-methionine Disulfate Tosylate Applications
- Pharmaceutical Drugs: Active pharmaceutical ingredient (API) in prescription medications for liver disease (hepatic cirrhosis), depression (MDD), osteoarthritis, and fibromyalgia treatment.
- Dietary Supplements: Key ingredient in premium nutraceutical supplements targeting joint health, mood support, liver health, and cognitive function in the global health supplement market.
- Mental Health Support: Clinically studied for antidepressant properties. Used as adjunct therapy and a standalone supplement for supporting mood, methylation pathways, and neurotransmitter synthesis.
- Liver Health: Widely used in hepatology for treatment of intrahepatic cholestasis, alcoholic liver disease, and non-alcoholic fatty liver disease (NAFLD) due to its hepatoprotective properties.
- Joint & Bone Health: Clinically proven as effective as NSAIDs in reducing osteoarthritis pain with fewer side effects, making it a preferred ingredient in joint health formulations.
S-Adenosyl-L-methionine Disulfate Tosylate Package & Storage
- Package:1kg/bag; 25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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